You asked: Are there any gender differences in the hippocampus volume after head size correction a volumetric and voxel based morphometric study?

Absolute hippocampal volumes were larger in men than women. After adjusting for head-size, the proportion method indicated larger hippocampi in women than men, while no gender differences were found using the GLM approach.

What is the volume of the hippocampus?

In adult humans the volume of the hippocampus on each side of the brain is about 3.0 to 3.5 cm3 as compared to 320 to 420 cm3 for the volume of the neocortex. There is also a general relationship between the size of the hippocampus and spatial memory.

What does increased hippocampal volume mean?

Increased hippocampal volume translates to improved memory function and higher serum BDNF. We also demonstrate that higher fitness levels are protective against loss of hippocampal volume.

What does decreased hippocampal volume mean?

The present findings emphasize that patients with reduced hippocampal volumes show more executive dysfunctions than their counterparts. Thus, the mechanisms resulting in reduced hippocampal volumes seem to be related to the development of major depression.

Why is hippocampal volume important?

This study reports that in healthy young males hippocampal volume is positively associated with declarative memory performance as tested by the CVLT. Measures of short-delay retention, long-delay retention and discriminability were significantly positively correlated with percent hippocampal volume.

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Does the size of your hippocampus matter?

It’s normal for the hippocampus to shrink as we age, but it’s much more pronounced in people with mild cognitive impairment or Alzheimer’s disease. Scientists long believed that a bigger hippocampus meant a better memory until a 2004 study showed that its size does not always matter for memory in older adults.

What does a smaller hippocampus mean?

A small hippocampus makes you more vulnerable to stress’s ill effects, including damage to the hippocampus. Particularly intriguing is the correlation the Reiss study found between high cortisol and progressive reductions in hippocampal volume over time.

What increases hippocampus?

The best way to generate new hippocampal neurons is to exercise. … Other studies have shown that people who exercise regularly and are physically fit have a much bigger hippocampus. The more you walk, the bigger your hippocampus will get and the less would be your risk for developing Alzheimer’s disease.

What stimulates the hippocampus?


Exercise, particularly aerobic exercise, is one of the best ways to boost BDNF levels and improve hippocampal function. For example, a now-famous study compared the brains of two groups of mice. One group had access to a running wheel, and one did not.

Does size of hippocampus affect memory?

The left hippocampal volume was found to be the only significant predictor of scores on LM in successful ageing; larger volumes were associated with superior memory performance.

How are the left and right hippocampus different?

Right hippocampus plays a critical role in spatial memory in older adults, while the role of left hippocampus in verbal memory is more prominent.

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What is hippocampus in the brain?

Hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. It is a plastic and vulnerable structure that gets damaged by a variety of stimuli. Studies have shown that it also gets affected in a variety of neurological and psychiatric disorders.

What causes hippocampus damage?

Damage to hippocampus can occur through many causes including head trauma, ischemia, stroke, status epilepticus and Alzheimer’s disease.

How does the hippocampus work with memory?

hippocampus, region of the brain that is associated primarily with memory. … The hippocampus is thought to be principally involved in storing long-term memories and in making those memories resistant to forgetting, though this is a matter of debate.